Ventolin is a bronchodilating agent based on salbutamol, relieves bronchospasm. It is used for the treatment of bronchial asthma, chronic obstructive pulmonary disease and chronic bronchitis. Selective beta-2-adrenomimetics. It has a relaxing effect on the smooth muscles of the bronchi.
Active component: 1 dose contains 100 mcg of salbutamol (salbutamol sulfate form).
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- relief of bronchial asthma attacks, including with exacerbation of severe bronchial asthma;
- prevention of bronchospasm attacks associated with allergen exposure or caused by physical exertion;
- use as one of the components in long-term maintenance therapy of bronchial asthma.
Chronic obstructive pulmonary disease (COPD), accompanied by reversible airway obstruction, including chronic bronchitis and pulmonary emphysema.
Salbutamol is a selective beta-2 adrenergic receptor antagonist. When using therapeutic doses, it affects the beta-2 adrenoreceptors of the smooth muscles of the bronchi. At the same time, the effect on the beta-1 adrenoreceptors of the myocardium is insignificant or absent. Salbutamol has a pronounced bronchodilating property. Its reception stops or prevents bronchial spasm, increases the vital capacity of the lungs and mucociliary clearance, reduces resistance in the respiratory tract, activates the functions of the atrial epithelium and stimulates mucus secretion.
When using the recommended doses, there is no negative effect on the cardiovascular system. Does not cause an increase in blood pressure. Provokes the expansion of the coronary arteries.
Salbutamol also reduces the concentration of potassium in the blood, affects the release of insulin, has a lipolytic and hyperglycemic effect. Increases the risk of acidosis.
The effect of inhalation appears after 5 minutes and lasts for 4-6 hours.
After inhalation, 10-20% of the salbutamol dose penetrates into the lower respiratory tract. The rest is deposited in the oropharynx and swallowed. Part of the drug deposited in the respiratory tract is absorbed into the lung tissue and blood, but is not metabolized in the lungs.
The ability of salbutamol to bind to blood proteins is 10%. The active ingredient that penetrates into the blood is metabolized in the liver and is excreted mainly in the urine in unchanged form. The swallowed part of the drug is absorbed from the gastrointestinal tract and metabolized when passing through the liver.
The aerosol is intended for inhalation. The treatment regimen is selected by the doctor. The maximum number of inhalations per day is 4. The need for more frequent use indicates a worsening of the course of the disease.
The following dosage regimen is provided for adults and children:
to eliminate an attack of bronchospasm: 1-2 inhalations;
to prevent bronchospasm caused by exposure to an allergen or physical activity: 2 inhalations 10-15 minutes before exposure to a provoking factor;
for long-term maintenance therapy: 2 inhalations 4 times a day.
The aerosol is intended for inhalation.
After opening the aerosol bottle should be thoroughly shaken and pressed on the valve to release one dose into the air. This is necessary to check the health of the inhaler. Such manipulation is also carried out after a long break in the use of the inhaler.
The algorithm of using the inhaler:
All manipulations are performed slowly.
The inhaler should be cleaned once a week. To do this, a metal canister is removed from the plastic case and the mouthpiece cover is removed. The case and lid are washed under a stream of warm water. After thoroughly drying the parts inside and out. Then a metal canister is placed in the case and the mouthpiece cover is put on. Do not immerse the metal canister in water.
The use of the drug in a dosage exceeding the recommended one may be accompanied by the development of undesirable symptoms. The most frequent of them are: decreased blood pressure, nausea and vomiting, hypokalemia, muscle tremor, tachycardia. Respiratory alkalosis, headache, agitation, decreased oxygen in the blood, increased serum glucose, hallucinations, dilation of peripheral vessels, tachyarrhythmia, ventricular flutter occur less frequently.
Cardioselective beta-blockers are used as antidotes for overdose. But care should be taken when using them in patients with a history of bronchospasm attacks. Since large doses of salbutamol can provoke hypokalemia, it is necessary to monitor the level of potassium in the blood when signs of overdose appear.
hypersensitivity to any component of the drug;
management of premature birth;
children under 2 years of age.
With caution: tachyarrhythmia, myocarditis, heart defects, aortic stenosis, coronary artery disease, severe chronic heart failure, hypertension, thyrotoxicosis, pheochromocytoma, decompensated diabetes mellitus, glaucoma, epipripad, renal or hepatic insufficiency, simultaneous administration of non-selective beta-blockers, pregnancy, lactation.
The appointment of inhalations of the drug Ventolin to women during pregnancy is advisable only when the expected benefit to the mother exceeds the possible risk to the fetus. Taking salbutamol-based medications during the mother's pregnancy can provoke malformations and abnormalities in the fetus, such as cleft palate or underdevelopment of the limbs.
With a high degree of probability, salbutamol penetrates into breast milk. Therefore, the use of the drug during lactation is not recommended. If there is a vital need for treatment, breastfeeding should be discontinued.
Consult your doctor before you decide to buy ventolin online!
Against the background of treatment with the drug Ventolin it is possible to develop side effects from various organs and systems of the body:
When prescribing the drug , it is necessary to take into account the following features of interaction with other drugs:
The aerosol for inhalation is available in an aluminum bottle equipped with a dosing device. There is a protective cap on the bottle. The drug, together with the instructions for use, is placed in a pack of cardboard.
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